Crossville Chronicle, Crossville, TN

Glade Sun

September 5, 2013

Raising awareness of Alzheimer’s disease

CROSSVILLE — Currently, there is no cure for Alzheimer's disease. However, drug and non-drug treatments may help with both cognitive and behavioral symptoms. The U.S. Food and Drug Administration (FDA) has approved two types of medications – cholinesterase inhibitors (Aricept, Exelon, Razadyne, Cognex) and memantine (Namenda) – to treat the cognitive symptoms (memory loss, confusion and problems with thinking and reasoning) of Alzheimer's disease. All of these drugs treat the early to moderate stages of Alzheimer’s.

As Alzheimer’s progresses, brain cells die and connections among cells are lost, causing cognitive symptoms to worsen. While current medications cannot stop the damage Alzheimer’s causes to brain cells, they may help lessen or stabilize symptoms for a limited time by affecting certain chemicals involved in carrying messages among the brain's nerve cells. Doctors sometimes prescribe both types of medications together. Some doctors also prescribe high doses of vitamin E for cognitive changes of Alzheimer's disease.

A quest is under way to find new treatments to stop, slow or even prevent Alzheimer's. Because new drugs take years to produce from concept to market; it is critical that Alzheimer's and related dementias research continue to accelerate.

Many of the new drugs in development aim to modify the disease process itself, by impacting one or more of the many wide-ranging brain changes that Alzheimer's causes. These changes offer potential "targets" for new drugs to stop or slow the progress of the disease. Many researchers believe successful treatment will eventually involve a "cocktail" of medications aimed at several targets, similar to current state-of-the-art treatments for many cancers and AIDS.

The following are examples of promising targets for next-generation drug therapies under investigation in current research studies:

Beta-amyloid is the chief component of plaques, one hallmark Alzheimer's brain abnormality.

Tau protein is the chief component of tangles, the other hallmark brain abnormality.

Inflammation is another key Alzheimer's brain abnormality.

Insulin resistance and the way brain cells process insulin may be linked to Alzheimer's disease.

Gauging treatment impact with brain imaging and biomarkers is a key to future success. In addition to investigating experimental drugs, many clinical trials in progress include various brain imaging studies and testing of blood or spinal fluid. Researchers hope these techniques will one day provide methods to diagnose Alzheimer's disease in its earliest, most treatable stages – possibly even before symptoms appear. Biomarkers may also eventually offer better methods to monitor response to treatment.

Raising Awareness and Supporting Alzheimer’s in Cumberland County

On Saturday, Sept. 7 Alzheimer’s of Tennessee will hold the second Annual Plateau Alzheimer’s Walk. You can participate as an individual or a team/group.  Note that all funds raised for this event directly support Alzheimer’s here in Cumberland County.  For more information view www.alztnevents.org or call Cyd Riede at 456-2122.

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Glade Sun
  • County residents urged to vote

    Cumberland County has around 39,000 registered voters, as well as a strong reputation for voter participation.  However, as of press time on Tuesday, only 4,300 residents had taken advantage of early voting for the Aug. 7 primary and general elections. Local officials are predicting less than 50 percent of registered voters will cast their vote in the 14 days of early voting, plus election day. Only 23 percent of registered county voters participated in the May elections.

    July 30, 2014

  • Board amends by-laws

    At the July meeting of the Fairfield Glade Community Club, the board of directors approved a vote to amend the club's bylaws regarding uncontested elections of board members, effectively declaring Bob Diller and Steven Smith new board members.

    July 30, 2014

  • Naiad Kuhlman.jpg Senior olympian on the run for good health

    No one can get away with telling Naiad Kuhlman of Crossville that age is a barrier to exercise. The avid runner, personal trainer and instructor at Cumberland Medical Center’s Wellness Complex at Fairfield Glade won’t buy the excuse.

    July 30, 2014 1 Photo

  • Enjoying nature.jpg Get your mink coat on the road

    It is interesting what animals you see crossing the roads sometimes. When animals cross roads, you can get a look at them, that wouldn't be possible if they stayed inside the cover of trees or grass. Sometimes, it is just a fleeting glance and you aren't sure what you saw. When you go into the woods looking for animals, they usually hide or leave the area before you even know they are around. But, roads are wide open with no cover. Also, most mammals are nocturnal, so they are out when we aren't. Anytime that I am on a two-lane road at night, I am always watching intently for wildlife in the headlights.

    July 30, 2014 1 Photo

  • Read the latest edition of "The Bulletin"

    The Crossville Chronicle-Glade Sun also publishes a newsletter called "The Bulletin" in which you'll find a schedule of Glade activities and events, a restaurant and dining guide, golf information, and even tour schedules. Click here for the latest PDF edition of "The Bulletin."

    April 21, 2010 1 Link

  • Patches of Life: The replacement years

    I need a new refrigerator. There are some other things on order too as we seem to be in the replacement year of our life. Everything from the light bulbs to the computer seemed to agree that this is the year of replacement.

    July 30, 2014

  • Abacus Column: Tennessee the third most corrupt state in the U.S.?

    According to a recent article in Time magazine, Tennessee is ranked third among U.S. States in political corruption. I am not sure how they measure such crime in order to make such a charge. Does some purveyor of statistics identify the number of elected officials proved guilty in a court of law; or merely charged with corruption?

    July 30, 2014

  • A Time 4 Paws celebrates pet adoption after 3 1/2 years

    Three and a half years ago, a local no-kill animal welfare organization known as A Time 4 Paws (AT4P) received an important email. A Nashville animal shelter volunteer asked if AT4P could take two severely abused English Pointer mixes. The email said they didn't want to take back two dogs they had placed in foster care for fear they would have to kill them.

    July 30, 2014

  • A Time 4 Paws collecting shoes to help Soles4Souls in fight against global poverty

    Attention anyone with a closet! Those shoes no longer wanted are desperately needed to fight the human tragedy of global poverty.
    That’s the message being delivered by A Time 4 Paws, which has launched an ongoing drive to collect shoes to help the poor. Used and new shoes can be dropped off at A Time 4 Paws in Crossville and can be left in the blue recycling bin outside labeled Soles4Souls.

    July 30, 2014

  • FFG Treasure Hunt set for Sept. 5

    The 2014 Fairfield Glade Treasure Hunt is set for Friday, Sept. 5. This has always been a fun evening for those who enjoy puzzle solving, figuring out clues or just having a good time.

    July 30, 2014

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